Transgenic and Knock Out Mice

The Flavell laboratory operates a facility that routinely generates transgenic mice by microinjection of blastocysts, and knockout mice by homologous recombination in embryonic stem cells followed by microinjection of the cells. Two full time staff operate this state-of-the-art facility. Many members of the Department of Immunobiology make use of this facility on a collaborative basis with Dr. Flavell.